The Nordic Rheumatic Diseases Strategy Trials And Registries Study

project manager


phd fellow

About the project

NORD-STAR is a multicenter randomized controlled trial being conducted in all Nordic countries and the Netherlands. A total of 812 patients with newly diagnosed arthritis are included.

Who can participate?

Inclusion of patients in the NORD-STAR study has been completed and all patients have completed the first part. Currently, long-term follow-up of the patients is ongoing with 5- and 10-year visits.

Project arrangement

The study compares the effect of conventional first-line treatment (methotrexate and prednisolone) with the effect of methotrexate combined with one of three different biologics in early RA. The three biological drugs are (certolizumab pegol (TNF inhibitor), abatacept (T-cell modulator) and tocilizumab (IL6 inhibitor). In addition, two different tapering strategies are compared in those who have a good response to treatment. NORD-STAR is the largest investigator-initiated randomized trial in newly diagnosed arthritis.


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