Alexander Mathiessen

Postdoc
https://orcid.org/0000-0002-9696-2081

See Google Scholar profile

See publications in PubMed

Education

Doctor (MD) at the Faculty of Medicine, University of Oslo (2004-2011)
Officer training at Forsvarets Sanitet (FSAN) (2013-2014)
Doctoral degree at the Faculty of Medicine, University of Oslo (2014-2017)

Position

Post.doc. (50%) in rheumatology, Diakonhjemmet hospital
Doctor in specialization (50%) internal medicine/rheumatology, Diakonhjemmet Hospital
Lecturer (10%) at the Faculty of Medicine, University of Oslo

Field of interest

Ultrasound of the musculoskeletal system
Ultrasound-guided injection technique (of joints, tendon sheaths, bursa, carpal tunnel syndrome, trigger finger)
Hand osteoarthritis
Biopsy of joints and synovial membranes
Personalized medicine
User participation in research
Randomized controlled trials
MRI of the knee and semi-automated measurement of cartilage thickness and volume (in collaboration with Harvard University, Boston, USA)

Other

In the management team of REMEDY Patient council (user participation in research)
In the management group for the Young Researcher Program and the Mobility program in REMEDY

Email

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Telephone

+47 97501889

visiting address

Diakonhjemmet hospital
Forstanderboligen
Reidar Kobros vei 8
0370 Oslo

Postal address

Diakohjemmet hospital
PO Box 23 Vinderen
0319 Oslo

Projects

WP1 - Optimized medical interventions

MERINO

Methotrexate in the treatment of erosive hand osteoarthritis

Project Manager:

Ida Bos-Haugen

Publications

Publications taken from the National Science Archive (NVA):

Associations of inflammatory and metabolic biomarkers with incident erosive hand osteoarthritis in the osteoarthritis initiative cohort

Timothy E. McAlindon, Jennifer L. Hunnicutt, Mary B. Roberts, Ida Kristin Bos-Haugen, Lena F. Schaefer, Jeffrey B. Driban

Osteoarthritis and Cartilage

2024

Gender differences in patterns of cartilage loss: Data from the Osteoarthritis Initiative

Rebecca Amesbury, Hedieh Ragati-Haghi, Alexander Mathiessen, Todd Laffaye, Rebekah I. Stein, Jamie E. Collins

Osteoarthritis and Cartilage

2024

Lessons learned from the PICASSO trial regarding ultrasound examinations of osteoarthritic hand joints performed by occupational therapists

Marthe Gløersen, Merete Hermann-Eriksen, Åshild Hove, Ingvild Kjeken, Alexander Mathiessen, Hilde Berner Hammer

Ultrasound in medicine

2024

Coagulopathy and adverse outcomes in hospitalized patients with COVID-19: results from the NOR-Solidarity trial

Thor Ueland, Annika Elisabet Michelsen, Anders Tveita, Trine Kåsine, Tuva Børresdatter Dahl, Ane-Kristine Finbråten

Research and Practice in Thrombosis and Haemostasis (RPTH)

2023

Radiographic joint space width in individuals with hand osteoarthritis: Are their “healthy” joints really healthy?

Alexander Mathiessen, Immanuel Onuoha, Rebecca Luh, Jeffrey B. Driban, Mary B. Roberts, Charles B. Eaton

Osteoarthritis and Cartilage

2023

Predicting total knee arthroplasty from ultrasonography using machine learning

Aleksei Tiulpin, Simo Saarakkala, Alexander Mathiessen, Hilde Berner Hammer, Ove Nord Furnes, Lars Nordsletten

Osteoarthritis and Cartilage Open

2022

Markers of cellular senescence are associated with persistent pulmonary pathology after COVID-19 infection

Tove Lekva, Thor Ueland, Bente Halvorsen, Sarah Louise Mikalsen Murphy, Anne Ma Dyrhol-Riise, Anders Aune Tveita

Infectious Diseases

2022

High Circulating Levels of the Homeostatic Chemokines CCL19 and CCL21 Predict Mortality and Disease Severity in COVID-19

Anders Aune Tveita, Sarah Louise Mikalsen Murphy, Jan Cato Holter, Anders Benjamin Kildal, Annika Elisabet Michelsen, Tøri Vigeland Lerum

Journal of Infectious Diseases

2022

Persistent T-cell exhaustion in relation to prolonged pulmonary pathology and death after severe COVID-19: Results from two Norwegian cohort studies

Marius Trøseid, Tuva Børresdatter Dahl, Jan Cato Holter, Anders Benjamin Kildal, Sarah Louise Mikalsen Murphy, Kuan Yang

Journal of Internal Medicine

2022

Study protocol for the follow-up examination of the Nor-Hand study: A hospital-based observational cohort study exploring pain and biomarkers in people with hand osteoarthritis

Marthe Gløersen, Pernille Steen Pettersen, Øystein Gunnar Maugesten, Elisabeth Mulrooney, Alexander Mathiessen, Heidi Gammelsrud

Osteoarthritis and Cartilage Open

2021

Neutrophil count predicts outcome in hospitalized COVID-19 patients. Results from the NOR-Solidarity trial

Trine Kåsine, Anne Margarita Dyrhol Riise, Andreas Barratt-Due, Anders Benjamin Kildal, Inge Christoffer Olsen, Katerina Nezvalova-Henriksen

Journal of Internal Medicine

2021

Cartilage Topography Assessment with Local Area Cartilage Segmentation (LACS) for Knee MRI

Alexander Mathiessen, Erin Ashbeck, Emily Huang, Jeffrey Duryea

Arthritis Care and Research

2021

Ultrasonography of Inflammatory and Structural Lesions in Hand Osteoarthritis: An Outcome Measures in Rheumatology Agreement and Reliability Study

Alexander Mathiessen, Hilde Berner Hammer, Lene Terslev, Marion C. Kortekaas, Maria A. D'Agostino, Ida Kristin Haugen

Arthritis Care and Research

2021

Urbanization and Knee Cartilage Growth Among Children and Adolescents in Western Kenya

Nicholas B Holowka, Ian J Wallace, Alexander Mathiessen, Robert Mang'eni Ojiambo, Paul Okutoyi, Steven Worthington

ACR Open Rheumatology

2021

Associations between joint pathologies and central sensitization in persons with hand osteoarthritis: Results from the Nor-Hand study

Pernille Steen Pettersen, Tuhina Neogi, Karin Magnusson, Alexander Mathiessen, Hilde Berner Hammer, Till Uhlig

Rheumatology

2021

Erosive Hand Osteoarthritis: Incidence and Predictive Characteristics Among Participants in the Osteoarthritis Initiative

Timothy E. McAlindon, Jeffrey B. Driban, M. Roberts, Jeffrey Duryea, Ida K. Haugen, Lena F. Schaefer

Arthritis & Rheumatology

2021

Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial

Andreas Barratt-Due, Inge Christoffer Olsen, Katerina Nezvalova-Henriksen, Trine Kåsine, Fridtjof Lund-Johansen, Hedda Benedicte Hoel

Annals of Internal Medicine

2021

Validity and diagnostic performance of fluorescence optical imaging measuring synovitis in hand osteoarthritis: baseline results from the Nor-Hand cohort

Øystein Gunnar Maugesten, Alexander Mathiessen, Hilde Berner Hammer, Sigrid Valen Hestetun, Tore Kristian Kvien, Till Uhlig

Arthritis Research & Therapy

2020

Relationship between cam morphology, hip symptoms, and hip osteoarthritis: the Musculoskeletal pain in Ullersaker STudy (MUST) cohort

Joanne L. Kemp, Nina Østerås, Alexander Mathiessen, Lars Nordsletten, Rintje Agricola, Jan H Waarsing

HIP International

2020

Associations Between Ultrasound-Detected Synovitis, Pain and Function in Interphalangeal and Thumb Base Osteoarthritis: Data From the Nor-Hand Study

Caroline Mehl Fjellstad, Alexander Mathiessen, Barbara Therese Slatkovsky Christensen, Tore Kristian Kvien, Hilde Berner Hammer, Ida Kristin Bos-Haugen

Arthritis care & research

2019

Biomarkers of cardiovascular risk across phenotypes of osteoarthritis

Sella Aarrestad Provan, Silvia Christin Hellerud Rollefstad, Eirik Ikdahl, Alexander Mathiessen, Inger Jorid Berg, IB Wilkinson

Biomed Central Rheumatology

2019

Smoking and alcohol use are associated with structural and inflammatory hand osteoarthritis features

Karin Magnusson, Alexander Mathiessen, Hilde Berner Hammer, Tore Kristian Kvien, Barbara Therese Slatkovsky Christensen, Bård Natvig

Scandinavian Journal of Rheumatology

2017

Ultrasound-detected osteophytes predict the development of radiographic and clinical features of hand osteoarthritis in the same finger joints 5 years later

Alexander Mathiessen, Barbara Therese Slatkovsky Christensen, Tore Kristian Kvien, Ida Kristin Haugen, Hilde Berner Hammer

RMD Open

2017

A hospital-based observational cohort study exploring pain and biomarkers in patients with hand osteoarthritis in Norway: The Nor-Hand protocol

Marthe Gløersen, Elisabeth Mulrooney, Alexander Mathiessen, Hilde Berner Hammer, Barbara Therese Slatkovsky Christensen, Karwan Faraj

BMJ Open

2017

Synovitis in osteoarthritis: Current understanding with therapeutic implications

Alexander Mathiessen, Philip G. Conaghan

Arthritis Research & Therapy

2017

Imaging of osteoarthritis (OA): What is new?

Alexander Mathiessen, Marco Amedeo Cimmino, Hilde Berner Hammer, Ida Kristin Haugen, Annamaria Iagnocco, Philip G. Conaghan

Baillière's Best Practice & Research : Clinical Rheumatology

2016

Synovitis and radiographic progression in non-erosive and erosive hand osteoarthritis: is erosive hand osteoarthritis a separate inflammatory phenotype?

Ida Kristin Haugen, Alexander Mathiessen, Barbara Therese Slatkovsky Christensen, Karin Magnusson, Pernille Helen Bøyesen, Sølve Sesseng

Osteoarthritis and Cartilage

2016

Ultrasound-detected inflammation predicts radiographic progression in hand osteoarthritis after 5 years

Alexander Mathiessen, Barbara Therese Slatkovsky Christensen, Tore Kristian Kvien, Hilde Berner Hammer, Ida Kristin Haugen

Annals of the Rheumatic Diseases

2016

Global ultrasound assessment of structural lesions in osteoarthritis: a reliability study by the OMERACT ultrasonography group on scoring cartilage and osteophytes in finger joints

Hilde Berner Hammer, A. Iagnocco, Alexander Mathiessen, E. Filippucci, Frédérique Gandjbakhch, MC Kortekaas

Annals of the Rheumatic Diseases

2016

The impact of newer biological disease modifying anti-rheumatic drugs on cardiovascular risk factors: A 12-month longitudinal study in rheumatoid arthritis patients treated with rituximab, abatacept and tociliziumab

Sella Aarrestad Provan, Inger Jorid Berg, Hilde Berner Hammer, Alexander Mathiessen, Tore Kristian Kvien, Anne Grete Semb

PLOS ONE

2015

Ultrasonographic assessment of osteophytes in 127 patients with hand osteoarthritis: exploring reliability and associations with MRI, radiographs and clinical joint findings

Alexander Mathiessen, Ida Kristin Haugen, Barbara Slatkowsky-Christensen, Pernille Helen Bøyesen, Tore Kristian Kvien, Hilde Berner Hammer

Annals of the Rheumatic Diseases

2013