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  • Doctor (MD) at the Faculty of Medicine, University of Oslo (2004-2011)
  • Officer training at Forsvarets Sanitet (FSAN) (2013-2014)
  • Doctoral degree at the Faculty of Medicine, University of Oslo (2014-2017)


  • Post.doc. (50%) in rheumatology, Diakonhjemmet hospital
  • Doctor in specialization (50%) internal medicine/rheumatology, Diakonhjemmet Hospital
  • Lecturer (10%) at the Faculty of Medicine, University of Oslo

Field of interest

  • Ultrasound of the musculoskeletal system
  • Ultrasound-guided injection technique (of joints, tendon sheaths, bursa, carpal tunnel syndrome, trigger finger)
  • Hand osteoarthritis
  • Biopsy of joints and synovial membranes
  • Personalized medicine
  • User participation in research
  • Randomized controlled trials
  • MRI of the knee and semi-automated measurement of cartilage thickness and volume (in collaboration with Harvard University, Boston, USA)


  • In the management team of REMEDY Patient council (user participation in research)
  • In the management group for the Young Researcher Program and the Mobility program in REMEDY


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visiting address

Diakonhjemmet hospital
Reidar Kobros vei 8
0370 Oslo

Postal address

Diakohjemmet hospital
PO Box 23 Vinderen
0319 Oslo


WP1 - Optimized medical interventions


Methotrexate in the treatment of erosive hand osteoarthritis

Project Manager:
Ida Bos-Haugen


Publications taken from the National Science Archive (NVA):

Associations of inflammatory and metabolic biomarkers with incident erosive hand osteoarthritis in the osteoarthritis initiative cohort

Timothy E. McAlindon, Jennifer L. Hunnicutt, Mary B. Roberts, Ida Kristin Bos-Haugen, Lena F. Schaefer, Jeffrey B. Driban

Osteoarthritis and Cartilage


Coagulopathy and adverse outcomes in hospitalized patients with COVID-19: results from the NOR-Solidarity trial

Thor Ueland, Annika Elisabet Michelsen, Anders Tveita, Trine Kåsine, Tuva Børresdatter Dahl, Ane-Kristine Finbråten

Research and Practice in Thrombosis and Haemostasis (RPTH)


Radiographic joint space width in individuals with hand osteoarthritis: Are their “healthy” joints really healthy?

Alexander Mathiessen, Immanuel Onuoha, Rebecca Luh, Jeffrey B. Driban, Mary B. Roberts, Charles B. Eaton

Osteoarthritis and Cartilage


Predicting total knee arthroplasty from ultrasonography using machine learning

Aleksei Tiulpin, Simo Saarakkala, Alexander Mathiessen, Hilde Berner Hammer, Ove Nord Furnes, Lars Nordsletten

Osteoarthritis and Cartilage Open


Markers of cellular senescence are associated with persistent pulmonary pathology after COVID-19 infection

Tove Lekva, Thor Ueland, Bente Halvorsen, Sarah Louise Mikalsen Murphy, Anne Ma Dyrhol-Riise, Anders Aune Tveita

Infectious Diseases


High Circulating Levels of the Homeostatic Chemokines CCL19 and CCL21 Predict Mortality and Disease Severity in COVID-19

Anders Aune Tveita, Sarah Louise Mikalsen Murphy, Jan Cato Holter, Anders Benjamin Kildal, Annika Elisabet Michelsen, Tøri Vigeland Lerum

Journal of Infectious Diseases


Persistent T-cell exhaustion in relation to prolonged pulmonary pathology and death after severe COVID-19: Results from two Norwegian cohort studies

Marius Trøseid, Tuva Børresdatter Dahl, Jan Cato Holter, Anders Benjamin Kildal, Sarah Louise Mikalsen Murphy, Kuan Yang

Journal of Internal Medicine


Study protocol for the follow-up examination of the Nor-Hand study: A hospital-based observational cohort study exploring pain and biomarkers in people with hand osteoarthritis

Marthe Gløersen, Pernille Steen Pettersen, Øystein Gunnar Maugesten, Elisabeth Mulrooney, Alexander Mathiessen, Heidi Gammelsrud

Osteoarthritis and Cartilage Open


Neutrophil count predicts outcome in hospitalized COVID-19 patients. Results from the NOR-Solidarity trial

Trine Kåsine, Anne Margarita Dyrhol Riise, Andreas Barratt-Due, Anders Benjamin Kildal, Inge Christoffer Olsen, Katerina Nezvalova-Henriksen

Journal of Internal Medicine


Cartilage Topography Assessment with Local Area Cartilage Segmentation (LACS) for Knee MRI

Alexander Mathiessen, Erin Ashbeck, Emily Huang, Jeffrey Duryea

Arthritis Care and Research


Ultrasonography of Inflammatory and Structural Lesions in Hand Osteoarthritis: An Outcome Measures in Rheumatology Agreement and Reliability Study

Alexander Mathiessen, Hilde Berner Hammer, Lene Terslev, Marion C. Kortekaas, Maria A. D'Agostino, Ida Kristin Haugen

Arthritis Care and Research


Urbanization and Knee Cartilage Growth Among Children and Adolescents in Western Kenya

Nicholas B Holowka, Ian J Wallace, Alexander Mathiessen, Robert Mang'eni Ojiambo, Paul Okutoyi, Steven Worthington

ACR Open Rheumatology


Associations between joint pathologies and central sensitization in persons with hand osteoarthritis: Results from the Nor-Hand study

Pernille Steen Pettersen, Tuhina Neogi, Karin Magnusson, Alexander Mathiessen, Hilde Berner Hammer, Till Uhlig



Erosive Hand Osteoarthritis: Incidence and Predictive Characteristics Among Participants in the Osteoarthritis Initiative

Timothy E. McAlindon, Jeffrey B. Driban, M. Roberts, Jeffrey Duryea, Ida K. Haugen, Lena F. Schaefer

Arthritis & Rheumatology


Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial

Andreas Barratt-Due, Inge Christoffer Olsen, Katerina Nezvalova-Henriksen, Trine Kåsine, Fridtjof Lund-Johansen, Hedda Benedicte Hoel

Annals of Internal Medicine


Validity and diagnostic performance of fluorescence optical imaging measuring synovitis in hand osteoarthritis: baseline results from the Nor-Hand cohort

Øystein Gunnar Maugesten, Alexander Mathiessen, Hilde Berner Hammer, Sigrid Valen Hestetun, Tore Kristian Kvien, Till Uhlig

Arthritis Research & Therapy


Relationship between cam morphology, hip symptoms, and hip osteoarthritis: the Musculoskeletal pain in Ullersaker STudy (MUST) cohort

Joanne L. Kemp, Nina Østerås, Alexander Mathiessen, Lars Nordsletten, Rintje Agricola, Jan H Waarsing

HIP International


Associations Between Ultrasound-Detected Synovitis, Pain and Function in Interphalangeal and Thumb Base Osteoarthritis: Data From the Nor-Hand Study

Caroline Mehl Fjellstad, Alexander Mathiessen, Barbara Therese Slatkovsky Christensen, Tore Kristian Kvien, Hilde Berner Hammer, Ida Kristin Bos-Haugen

Arthritis care & research


Biomarkers of cardiovascular risk across phenotypes of osteoarthritis

Sella Aarrestad Provan, Silvia Christin Hellerud Rollefstad, Eirik Ikdahl, Alexander Mathiessen, Inger Jorid Berg, IB Wilkinson

Biomed Central Rheumatology


Smoking and alcohol use are associated with structural and inflammatory hand osteoarthritis features

Karin Magnusson, Alexander Mathiessen, Hilde Berner Hammer, Tore Kristian Kvien, Barbara Therese Slatkovsky Christensen, Bård Natvig

Scandinavian Journal of Rheumatology


Ultrasound-detected osteophytes predict the development of radiographic and clinical features of hand osteoarthritis in the same finger joints 5 years later

Alexander Mathiessen, Barbara Therese Slatkovsky Christensen, Tore Kristian Kvien, Ida Kristin Haugen, Hilde Berner Hammer

RMD Open


A hospital-based observational cohort study exploring pain and biomarkers in patients with hand osteoarthritis in Norway: The Nor-Hand protocol

Marthe Gløersen, Elisabeth Mulrooney, Alexander Mathiessen, Hilde Berner Hammer, Barbara Therese Slatkovsky Christensen, Karwan Faraj

BMJ Open


Synovitis in osteoarthritis: Current understanding with therapeutic implications

Alexander Mathiessen, Philip G. Conaghan

Arthritis Research & Therapy


Imaging of osteoarthritis (OA): What is new?

Alexander Mathiessen, Marco Amedeo Cimmino, Hilde Berner Hammer, Ida Kristin Haugen, Annamaria Iagnocco, Philip G. Conaghan

Baillière's Best Practice & Research : Clinical Rheumatology


Synovitis and radiographic progression in non-erosive and erosive hand osteoarthritis: is erosive hand osteoarthritis a separate inflammatory phenotype?

Ida Kristin Haugen, Alexander Mathiessen, Barbara Therese Slatkovsky Christensen, Karin Magnusson, Pernille Helen Bøyesen, Sølve Sesseng

Osteoarthritis and Cartilage


Ultrasound-detected inflammation predicts radiographic progression in hand osteoarthritis after 5 years

Alexander Mathiessen, Barbara Therese Slatkovsky Christensen, Tore Kristian Kvien, Hilde Berner Hammer, Ida Kristin Haugen

Annals of the Rheumatic Diseases


Global ultrasound assessment of structural lesions in osteoarthritis: a reliability study by the OMERACT ultrasonography group on scoring cartilage and osteophytes in finger joints

Hilde Berner Hammer, A. Iagnocco, Alexander Mathiessen, E. Filippucci, Frédérique Gandjbakhch, MC Kortekaas

Annals of the Rheumatic Diseases


The impact of newer biological disease modifying anti-rheumatic drugs on cardiovascular risk factors: A 12-month longitudinal study in rheumatoid arthritis patients treated with rituximab, abatacept and tociliziumab

Sella Aarrestad Provan, Inger Jorid Berg, Hilde Berner Hammer, Alexander Mathiessen, Tore Kristian Kvien, Anne Grete Semb



Ultrasonographic assessment of osteophytes in 127 patients with hand osteoarthritis: exploring reliability and associations with MRI, radiographs and clinical joint findings

Alexander Mathiessen, Ida Kristin Haugen, Barbara Slatkowsky-Christensen, Pernille Helen Bøyesen, Tore Kristian Kvien, Hilde Berner Hammer

Annals of the Rheumatic Diseases