Education

Can.med., University of Oslo (professional study in medicine)

Position

PhD fellow, Clinic for Rheumatology, Outpatient Clinic and Research, Diakonhjemmet Hospital

Field of interest

Rheumatology
Immunosuppressive medications
Personalized medicine
Therapeutic drug monitoring
Immunogenicity
Randomized controlled trials

Email

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Telephone

+47 98639267

visiting address

Diakonhjemmet hospital
Forstanderboligen
Reidar Kobros vei 8
0370 Oslo

Postal address

Diakohjemmet hospital
PO Box 23 Vinderen
0319 Oslo

Projects

WP2 - PPhenotyping for personalized medicine

NOR DRUM

The Norwegian study for therapeutic drug monitoring

Project Manager:

Espen A. Haavardsholm

WP1 - Optimized medical interventions

SQUEEZE

Maximizing the effect of prescription drugs in rheumatoid arthritis

Project Manager:

Espen A. Haavardsholm

Publications

Publications taken from the National Science Archive (NVA):

Clinical consequences of infliximab immunogenicity and the effect of proactive therapeutic drug monitoring: exploratory analyzes of the randomised, controlled NOR-DRUM trials

Marthe Kirkesæther Brun, Johanna Gehin, Kristin Reine Hammersbøen, David Warren, Rolf Klaasen, Joseph Sexton

The Lancet Rheumatology

2024

PhD dissertations

Knut Ørnes Brodahl, Marthe Kirkesæther Brun, Camilla Maria Falch, Trym Thune Flygel, Bente Johnsen, Kari Vatne Monsen

Journal of the Norwegian Medical Association

2024

HLA-DQ2 is associated with anti-drug antibody formation to infliximab in patients with immune-mediated inflammatory diseases

Marthe Kirkesæther Brun, Kristin Reine Hammersbøen, Marte Kathrine Viken, Grethe-Elisabeth Stenvik, Rolf Klaasen, Johanna Gehin

Journal of Internal Medicine

2023

Assessing Immunogenicity of Biologic Drugs in Inflammatory Joint Diseases: Progress Towards Personalized Medicine

Johanna Elin Gehin, Guro Løvik Goll, Marthe Kirkesæther Brun, Meghna Jani, Nils Bolstad, Silje Watterdal Syversen

BioDrugs

2022

Risk factors for anti-drug antibody formation to infliximab: Secondary analyzes of a randomized controlled trial

Marthe Kirkesæther Brun, Guro Løvik Goll, Kristin Kaasen Jørgensen, Joseph Sexton, Johanna Elin Gehin, Øystein Sandanger

Journal of Internal Medicine

2022

Effect of Therapeutic Drug Monitoring vs Standard Therapy During Maintenance Infliximab Therapy on Disease Control in Patients With Immune-Mediated Inflammatory Diseases: A Randomized Clinical Trial

Silje Watterdal Syversen, Kristin Kaasen Jørgensen, Guro Løvik Goll, Marthe Kirkesæther Brun, Øystein Sandanger, Kristin Reine Hammersbøen

Journal of the American Medical Association (JAMA)

2021

Effect of Therapeutic Drug Monitoring vs Standard Therapy During Infliximab Induction on Disease Remission in Patients With Chronic Immune-Mediated Inflammatory Diseases: A Randomized Clinical Trial

Silje Watterdal Syversen, Guro Løvik Goll, Kristin Kaasen Jørgensen, Øystein Sandanger, Joseph Sexton, Inge Christoffer Olsen

Journal of the American Medical Association (JAMA)

2021

Forced medication in mental health care - a systematic literature review

Marthe Kirkesæther Brun, Tonje Lossius Husum, Reidar Pedersen

Journal of the Norwegian Psychological Association

2017