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Education

  • Doctor (MD) at the Faculty of Medicine, University of Oslo (2007)
  • Doctoral degree (PhD) at the Faculty of Medicine, University of Oslo (2012)

Position

  • Senior researcher, Clinic for rheumatology, outpatient clinic and research, Diakonhjemmet hospital
  • Doctor in specialization Clinic for Medicine, Diakonhjemmet Hospital
  • Lecturer, University of Oslo

Field of interest

  • Osteoarthritis
  • Epidemiology
  • Pain by rheumatic disease
  • Validation of outcome measures
  • Image diagnostics
  • Randomized controlled trials

Other

  • Leader of work package 3 in REMEDY (Pain mechanisms and treatment)
  • Research prize for women's health from the 1.6 million club (2022)
  • OARSI Rising Star (2021)
  • Research award for young researchers from the Norwegian Scandinavian Association (2016)

Email

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Telephone

visiting address

Diakonhjemmet hospital
Forstanderboligen
Reidar Kobros vei 8
0370 Oslo

Postal address

Diakohjemmet hospital
PO Box 23 Vinderen
0319 Oslo

Projects

WP2 - PPhenotyping for personalized medicine

MDR-RA

The Norwegian study for therapeutic drug monitoring

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WP1 - Optimized medical interventions

MERINO

Methotrexate in the treatment of erosive hand osteoarthritis

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WP6 - Dechiphering long-term outcomes

NOR-DMARD

The Norwegian register for antirheumatic drugs

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WP3 - Pain mechanisms and management

Nor-Hand

Longitudinal observational study of people with hand osteoarthritis

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WP7 - Empowering the individual

Development of a care pathway for patients with hand osteoarthritis

Development of a course of treatment for patients with hand osteoarthritis

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WP1 - Optimized medical interventions

PICASSO

Treatment of painful inflammatory carpometacarpal-1 osteoarthritis with intra-articular steroids, saline or occupational therapy

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WP3 - Pain mechanisms and management

Pain following inflammatory joint diseases

To what extent are factors such as central sensitization, psychological strain, gender and systemic biomarkers associated with higher symptom strain?

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Publications

Publications taken from the National Science Archive (NVA):

Can gait patterns be explained by joint structure in people with and without radiographic knee osteoarthritis? Data from the IMI-APPROACH cohort

2024

Associations of inflammatory and metabolic biomarkers with incident erosive hand osteoarthritis in the osteoarthritis initiative cohort

2024

Erosive hand osteoarthritis and sarcopenia: data from the Osteoarthritis Initiative cohort

2024

A perspective on the evolution of semi-quantitative MRI assessment of osteoarthritis: Past, present and future

2024

Assessing the association of epigenetic age acceleration with osteoarthritis in the Multicenter Osteoarthritis Study (MOST)

2024

“You don't put it down to arthritis”: A qualitative study of the first symptoms recalled by individuals with knee osteoarthritis

2024

Severity and progression of structural hand OA is not associated with progression of structural knee OA: The IMI-APPROACH cohort

2024

Hand osteoarthritis phenotypes based on a biopsychosocial approach, and their associations with cross-sectional and longitudinal pain

2024

2023 EULAR classification criteria for hand osteoarthritis

2024

Lessons learned from the PICASSO trial regarding ultrasound examinations of osteoarthritic hand joints performed by occupational therapists

2024

The natural history of marginal erosions in hands with and without osteoarthritis

2024

Fluctuation of Bone Marrow Lesions and Inflammatory MRI Markers over 2 Years and Concurrent Associations with Quantitative Cartilage Loss

2024

Longitudinal stability of molecular endotypes of knee osteoarthritis patients

2024

Colchicine twice a day for hand osteoarthritis (COLOR): a double-blind, randomised, placebo-controlled trial

2023

Hand joints without radiographic osteoarthritis maintain their joint space width over 4 years despite what's happening elsewhere in the hand

2023

Comparative effectiveness of pharmacological interventions for hand osteoarthritis: A systematic review and network meta-analysis of randomized trials

2023

Machine-learning predicted and actual 2-year structural progression in the IMI-APPROACH cohort

2023

Development and validation of a machine learning-supported strategy of patient selection for osteoarthritis clinical trials: the IMI-APPROACH study

2023

Associations between pain sensitization and measures of physical function in people with hand osteoarthritis: Results from the Nor-Hand study

2023

A scoping review of how early-stage knee osteoarthritis has been defined

2023

Comorbidities in people with hand OA and their associations with pain severity and sensitization: Data from the longitudinal Nor-Hand study

2023

Automatic measuring of finger joint space width on hand radiograph using deep learning and conventional computer vision methods

2023

Quantitative CT of the knee in the IMI-APPROACH osteoarthritis cohort: Association of bone mineral density with radiographic disease severity, meniscal coverage and meniscal extrusion

2023

Exploring the differences between radiographic joint space width and MRI cartilage thickness changes using data from the IMI-APPROACH cohort

2023

Deep Learning for Predicting Progression of Patellofemoral Osteoarthritis Based on Lateral Knee Radiographs, Demographic Data and Symptomatic Assessments

2023

Prolonged morning stiffness is common in hand OA and does not preclude a diagnosis of hand osteoarthritis

2022

Predicted and actual 2-year structural and pain progression in the IMI-APPROACH knee osteoarthritis cohort

2022

The associations of psychological symptoms and cognitive patterns with pain and pain sensitization in people with hand osteoarthritis

2022

Test–retest precision and longitudinal cartilage thickness loss in the IMI-APPROACH cohort

2022

Structural tissue damage and 24-month progression of semi-quantitative MRI biomarkers of knee osteoarthritis in the IMI-APPROACH cohort

2022

Multimodal Multidisciplinary Management of Patients with Moderate to Severe Pain in Knee Osteoarthritis: A Need to Meet Patient Expectations

2022

The genetic contribution to hand osteoarthritis

2022

Prevalence, Incidence, and Progression of Radiographic and Symptomatic Hand Osteoarthritis: The Osteoarthritis Initiative

2022

The association of the lipid profile with knee and hand osteoarthritis severity: the IMI-APPROACH cohort

2022

Management of hand osteoarthritis: from an US evidence-based medicine guideline to a European patient-centric approach

2022

Osteoarthritis endotype discovery via clustering of biochemical marker data

2022

Racket or Bat Sports: No Association With Thumb-Base Osteoarthritis

2022

Development of radiographic classification criteria for hand osteoarthritis: a methodological report (Phase 2)

2022

Associations of Body Mass Index With Pain and the Mediating Role of Inflammatory Biomarkers in People With Hand Osteoarthritis

2022

GaitSmart motion analysis compared to commonly used function outcome measures in the IMI-APPROACH knee osteoarthritis cohort

2022

Associations of pain sensitization with tender and painful joint counts in people with hand osteoarthritis: results from the Nor-Hand study

2022

Study protocol for the follow-up examination of the Nor-Hand study: A hospital-based observational cohort study exploring pain and biomarkers in people with hand osteoarthritis

2021

Neuropathic pain in the IMI-APPROACH knee osteoarthritis cohort: prevalence and phenotyping

2021

Associations between Fluorescence Optical Imaging and Magnetic Resonance Imaging and symptoms in hand osteoarthritis.

2021

Baseline clinical characteristics of predicted structural and pain progressors in the IMI-APPROACH knee OA cohort

2021

Associations between joint pathologies and central sensitization in persons with hand osteoarthritis: Results from the Nor-Hand study

2021

Characteristics of persons with hand osteoarthritis visiting complementary and alternative medicine providers

2021

Comparison of 2 Postoperative Therapy Regimens After Trapeziectomy due to Osteoarthritis: A Randomized, Controlled Trial

2021

Metabolic syndrome and osteoarthritis distribution in the hand joints: A propensity score matching analysis from the osteoarthritis initiative

2021

Erosive Hand Osteoarthritis: Incidence and Predictive Characteristics Among Participants in the Osteoarthritis Initiative

2021

Core outcome measurement instrument selection for physical function in hand osteoarthritis using the OMERACT Filter 2.1 process

2021

Reliability and agreement of proton density-weighted vs. gadolinium-enhanced T1-weighted MRI in hand osteoarthritis. An OMERACT MRI special interest group reliability exercise

2021

Task shifting in the care of patients with hand osteoarthritis. Protocol for a randomized controlled non-inferiority trial

2021

Get a Grip on Factors Related to Grip Strength in Persons With Hand Osteoarthritis: Results From an Observational Cohort Study

2021

Evaluation of three scoring methods for Fluorescence Optical Imaging in erosive hand osteoarthritis and rheumatoid arthritis

2020

Non-surgical management of knee osteoarthritis: comparison of ESCEO and OARSI 2019 guidelines

2020

Association between Race and Radiographic, Symptomatic, and Clinical Hand Osteoarthritis: A Propensity Score-Matched Study Using Osteoarthritis Initiative Data

2020

Relationship between motion, using the GaitSmartTM system, and radiographic knee osteoarthritis: an exploratory analysis in the IMI-APPROACH cohort

2020

Development of classification criteria for hand osteoarthritis: comparative analyzes of persons with and without hand osteoarthritis

2020

Validity and diagnostic performance of fluorescence optical imaging measuring synovitis in hand osteoarthritis: baseline results from the Nor-Hand cohort

2020

Cohort profile: The Applied Public-Private Research enabling OsteoArthritis Clinical Headway (IMI-APPROACH) study: a 2-year, European, cohort study to describe, validate and predict phenotypes of osteoarthritis using clinical, imaging and biochemical markers

2020

Detection of subclinical skin manifestation in patients with psoriasis and psoriatic arthritis by fluorescence optical imaging

2020

Patient Goals and Motivation for Thumb Carpometacarpal Osteoarthritis Surgery

2020

Associations Between Radiographic and Ultrasound‐Detected Features in Hand Osteoarthritis and Local Pressure Pain Thresholds

2020

Report from the Hand Osteoarthritis Working Group at OMERACT 2018: Update on Core Instrument Set Development

2019

OARSI Guidelines for the Non-Surgical Management of Knee, Hip, and Polyarticular Osteoarthritis

2019

Associations Between Ultrasound-Detected Synovitis, Pain and Function in Interphalangeal and Thumb Base Osteoarthritis: Data From the Nor-Hand Study

2019

Fluorescence Optical Imaging for Treatment Monitoring in Patients With Early and Active Rheumatoid Arthritis in a 1-year Follow-Up Period

2019

Does occupational therapy delay or reduce the proportion of patients who receive thumb carpometacarpal joint surgery? A multicentre randomized controlled trial

2019

The OMERACT MRI in enthesitis initiative: Definitions of key pathologies, suggested MRI sequences, and a novel heel enthesitis scoring system

2019

Cartilage evaluation in finger joints in healthy controls and early hand osteoarthritis patients using high-resolution MRI

2019

Biomarkers of cardiovascular risk across phenotypes of osteoarthritis

2019

Validation of the intermittent and constant osteoarthritis pain questionnaire in patients with hand osteoarthritis: Results from the NOR-HAND study

2019

Swollen, but not tender joints, are independently associated with ultrasound synovitis: Results from a longitudinal observational study of patients with established rheumatoid arthritis

2019

Peripheral and Central Sensitization of Pain in Individuals With Hand Osteoarthritis and Associations With Self-Reported Pain Severity

2019

Non-pharmacological treatment gap preceding surgical consultation in thumb carpometacarpal osteoarthritis- A cross-sectional study

2019

Heberden's Nodes and Knee Osteoarthritis–Related Osseous Structural Damage: Exploratory Study From the Osteoarthritis Initiative

2019

Characteristics of Accelerated Hand Osteoarthritis: Data from the Osteoarthritis Initiative

2019

Guidelines for the conduct of pharmacological clinical trials in hand osteoarthritis: Consensus of a Working Group of the European Society on Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO)

2018

Longitudinal reliability of the OMERACT thumb base osteoarthritis magnetic resonance imaging scoring system (TOMS)

2018

Phase IIa, placebo-controlled, randomized study of lutikizumab, an anti-interleukin-1α and anti-interleukin-1β dual variable domain immunoglobulin, in patients with erosive hand osteoarthritis

2018

A randomized double-blind placebo-controlled crossover trial of HUMira (adalimumab) for erosive hand Osteoarthritis – the HUMOR trial

2018

Enhanced angiogenesis and increased bone turnover characterize bone marrow lesions in osteoarthritis at the base of the thumb

2018

Association of Quantitative and Topographic Assessment of Heberden's Nodes With Knee Osteoarthritis: Data From the Osteoarthritis Initiative

2018

Atlas for the OMERACT thumb base osteoarthritis MRI scoring system (TOMS)

2018

Incident hand OA is strongly associated with reduced peripheral blood leukocyte telomere length

2018

2018 update of the EULAR recommendations for the management of hand osteoarthritis

2018

Trabecular bone texture detected by plain radiography is associated with MRI-defined osteophytes in finger joints of women without radiographic osteoarthritis

2018

Association Between Metabolic Syndrome and Radiographic Hand Osteoarthritis: Data From a Community-Based Longitudinal Cohort Study

2018

The associations between radiographic hand osteoarthritis definitions and hand pain: data from the osteoarthritis initiative

2017

Validation of a knowledge transfer tool for the knee inflammation MRI scoring system for bone marrow lesions according to the OMERACT filter: Data from the osteoarthritis initiative

2017

Validation of a Knowledge Transfer Tool According to the OMERACT Filter: Does Web-based Real-time Iterative Calibration Enhance the Evaluation of Bone Marrow Lesions in Hip Osteoarthritis?

2017

The prevalence, incidence, and progression of hand osteoarthritis in relation to body mass index, smoking, and alcohol consumption

2017

Smoking and alcohol use are associated with structural and inflammatory hand osteoarthritis features

2017

Ultrasound-detected osteophytes predict the development of radiographic and clinical features of hand osteoarthritis in the same finger joints 5 years later

2017

A hospital-based observational cohort study exploring pain and biomarkers in patients with hand osteoarthritis in Norway: The Nor-Hand protocol

2017

Long term type 1 diabetes is associated with hand pain, disability and stiffness but not with structural hand osteoarthritis features - The Dialong hand study

2017

The comparison of magnetic resonance imaging and radiographs to assess structural progression over 5 years in hand osteoarthritis

2017

Frequency of temporomandibular joint osteoarthritis and related symptoms in a hand osteoarthritis cohort

2017