Longitudinal observational study of people with hand osteoarthritis

project manager

About the project

Hand osteoarthritis is a disease that affects a large proportion of the population, particularly women. Hand osteoarthritis can cause significant problems in the form of pain, reduced function and stiffness. There is currently no treatment that can prevent or delay the progression of the disease.

The aim of the project is to better understand the causes of pain in people with hand osteoarthritis, and to study different disease markers, such as imaging and patient-reported outcome measures. In the long term, this will provide a better basis for alleviating patients' pain and increased knowledge of underlying disease mechanisms.

Who can participate?

The study includes adult patients with hand osteoarthritis who have been referred to or are being followed at the rheumatology outpatient clinic at Diakonhjemmet Hospital.

Recruitment of new participants in the study has been completed.

Project arrangement

Participants have been examined at two time points (2016-17 and 2019-21). 300 patients completed the examinations in 2016-17, while 213 participated in 2019-21 (of these, 206 completed the clinical examination).

Participants completed various questionnaires, underwent a clinical examination, pain sensitivity tests, blood and urine tests, and various imaging tests such as X-rays, MRI and ultrasound.


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