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Nor-Hand
Longitudinal observational study of people with hand osteoarthritis
Project Manager
Post doc
PhD fellow
ABOUT THE PROJECT
Hand arthritis is a disease that affects a large proportion of the population, and women in particular. Hand osteoarthritis can cause significant problems in the form of pain, reduced function and stiffness. There is currently no treatment that can prevent or delay the development of the disease.
The project's aim is to better understand the causes of pain in people with hand osteoarthritis, and to study various disease markers, such as imaging and patient-reported outcome measures. In the long term, this will provide a better basis for being able to relieve the patients' pain and increased knowledge of underlying disease mechanisms.
WHO CAN JOIN?
The study includes adult patients with hand osteoarthritis who have been referred or followed up at the rheumatology outpatient clinic at Diakonhjemmet Hospital.
Recruitment of new participants in the study has ended.
WHAT DOES THE STUDY INCLUDE?
The participants have been examined at two instances (2016-17 and 2019-21). 300 patients completed the examinations in 2016-17, while 213 participated in 2019-21 (of these, 206 completed a clinical examination).
The participants have filled in various questionnaires, undergone a clinical examination, carried out tests to assess pain sensitivity, taken blood samples and submitted a urine sample, and taken various imaging examinations such as X-ray, MRI and ultrasound.
PUBLICATIONS
Items 1-19 of 19 ( Display the 19 citations in PubMed )
1. |
Mulrooney E, Neogi T, Dagfinrud H, Hammer HB, Pettersen PS, Kvien TK, Magnusson K, Haugen IK. Osteoarthritis Cartilage. 2024 Apr 30:S1063-4584(24)01168-3. doi: 10.1016/j.joca.2024.04.011. Online ahead of print. PMID: 38697510 |
2. |
Gløersen M, Steen Pettersen P, Neogi T, Sexton J, Kvien TK, Hammer HB, Haugen IK. Osteoarthritis Cartilage. 2023 Oct;31(10):1388-1395. doi: 10.1016/j.joca.2023.07.005. Epub 2023 Jul 24. PMID: 37495183 |
3. |
Mulrooney E, Neogi T, Dagfinrud H, Hammer HB, Pettersen PS, Gløersen M, Kvien TK, Magnusson K, Haugen IK. Osteoarthr Cartil Open. 2023 May 5;5(3):100367. doi: 10.1016/j.ocarto.2023.100367. eCollection 2023 Sep. PMID: 37234862 Free PMC article. |
4. |
Mulrooney E, Neogi T, Dagfinrud H, Hammer HB, Pettersen PS, Gaarden TL, Engedal K, Kvien TK, Magnusson K, Haugen IK. Osteoarthr Cartil Open. 2022 May 6;4(2):100267. doi: 10.1016/j.ocarto.2022.100267. eCollection 2022 Jun. PMID: 36475288 Free PMC article. |
5. |
Ulrichsen M, Kristoffersen AE, Kjeken I, Haugen IK. Osteoarthr Cartil Open. 2021 Nov 17;3(4):100220. doi: 10.1016/j.ocarto.2021.100220. eCollection 2021 Dec. PMID: 36474754 Free PMC article. |
6. |
Gløersen M, Steen Pettersen P, Neogi T, Jafarzadeh SR, Vistnes M, Thudium CS, Bay-Jensen AC, Sexton J, Kvien TK, Hammer HB, Haugen IK. Arthritis Rheumatol. 2022 May;74(5):810-817. doi: 10.1002/art.42056. Epub 2022 Mar 23. PMID: 35137553 Free PMC article. |
7. |
Gløersen M, Steen Pettersen P, Neogi T, Slatkowsky-Christensen B, Kvien TK, Magnusson K, Hammer HB, Haugen IK. RMD Open. 2022 Jan;8(1):e001774. doi: 10.1136/rmdopen-2021-001774. PMID: 34987090 Free PMC article. |
8. |
Steen Pettersen P, Neogi T, Magnusson K, Mathiessen A, Hammer HB, Uhlig T, Kvien TK, Haugen IK. Rheumatology (Oxford). 2022 May 30;61(6):2316-2324. doi: 10.1093/rheumatology/keab708. PMID: 34559196 Free PMC article. |
9. |
Gløersen M, Steen Pettersen P, Maugesten Ø, Mulrooney E, Mathiessen A, Gammelsrud H, Hammer HB, Neogi T, Ohrndorf S, Faraj K, Sjølie D, Slatkowsky-Christensen B, Kvien TK, Haugen IK. Osteoarthr Cartil Open. 2021 Jul 30;3(3):100198. doi: 10.1016/j.ocarto.2021.100198. eCollection 2021 Sep. PMID: 36474811 Free PMC article. |
10. |
Maugesten Ø, Pedersen SJ, Stoenoiu MS, Kroon F, Mathew AJ, Genant HK, Conaghan PG, Gandjbakhch F, Kloppenburg M, Peterfy C, Østergaard M, Haugen IK. Semin Arthritis Rheum. 2021 Aug;51(4):929-932. doi: 10.1016/j.semarthrit.2021.05.007. Epub 2021 May 21. PMID: 34140182 |
11. |
Maugesten Ø, Ohrndorf S, Slatkowsky-Christensen B, Kvien TK, Uhlig T, Haugen IK. Rheumatology (Oxford). 2022 Feb 2;61(2):764-769. doi: 10.1093/rheumatology/keab085. PMID: 33521807 |
12. |
Maugesten Ø, Mathiessen A, Hammer HB, Hestetun SV, Kvien TK, Uhlig T, Ohrndorf S, Haugen IK. Arthritis Res Ther. 2020 May 1;22(1):98. doi: 10.1186/s13075-020-02185-0. PMID: 32357904 Free PMC article. |
13. |
Maugesten Ø, Ohrndorf S, Glinatsi D, Ammitzbøll-Danielsen M, Kisten Y, Østergaard M, Terslev L, Uhlig T, Kvien TK, Haugen IK. Osteoarthr Cartil Open. 2019 Dec 9;1(3-4):100017. doi: 10.1016/j.ocarto.2019.100017. eCollection 2020 Jan-Feb. PMID: 36475004 Free PMC article. |
14. |
Haugen IK, Aaserud J, Kvien TK. Arthritis Care Res (Hoboken). 2021 Jun;73(6):794-800. doi: 10.1002/acr.24385. PMID: 32702166 |
15. |
Steen Pettersen P, Neogi T, Magnusson K, Hammer HB, Uhlig T, Kvien TK, Haugen IK. Arthritis Rheumatol. 2020 Jun;72(6):966-971. doi: 10.1002/art.41199. Epub 2020 Apr 26. PMID: 31904188 Free PMC article. |
16. |
Fjellstad CM, Mathiessen A, Slatkowsky-Christensen B, Kvien TK, Hammer HB, Haugen IK. Arthritis Care Res (Hoboken). 2020 Nov;72(11):1530-1535. doi: 10.1002/acr.24047. PMID: 31421023 |
17. |
Gløersen M, Steen Pettersen P, Kvien TK, Haugen IK. J Rheumatol. 2019 Jun;46(6):645-651. doi: 10.3899/jrheum.180835. Epub 2019 Mar 15. PMID: 30877221 |
18. |
Steen Pettersen P, Neogi T, Magnusson K, Berner Hammer H, Uhlig T, Kvien TK, Haugen IK. Arthritis Rheumatol. 2019 Jul;71(7):1070-1077. doi: 10.1002/art.40850. Epub 2019 May 14. PMID: 30741501 Free PMC article. |
19. |
Gløersen M, Mulrooney E, Mathiessen A, Hammer HB, Slatkowsky-Christensen B, Faraj K, Isaksen T, Neogi T, Kvien TK, Magnusson K, Haugen IK. BMJ Open. 2017 Sep 24;7(9):e016938. doi: 10.1136/bmjopen-2017-016938. PMID: 28947452 Free PMC article. |