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Joseph Sexton

Senior researcher | Statistician

Education

  • Major at the Department of Mathematics, Department of Statistics, University of Oslo (1997)
  • Doctoral degree (PhD) at the Department of Basic Medical Sciences, Department of Biostatistics, University of Oslo (2008)

Position

  • Senior researcher, Clinic for rheumatology, outpatient clinic and research, Diakonhjemmet Hospital

Field of interest

  • Clinical studies and design
  • Data analysis
  • Programming
  • Machine learning

Email

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Email

visiting address

Diakonhjemmet hospital
Forstanderboligen
Reidar Kobros vei 8
0370 Oslo

Postal address

Diakohjemmet hospital
PO Box 23 Vinderen
0319 Oslo

Projects

WP1 - Optimized medical interventions

ARCTIC

Remission in patients with rheumatoid arthritis: a randomized controlled trial investigating the use of ultrasound in clinical follow-up

Project Manager:
Espen A. Haavardsholm
WP1 - Optimized medical interventions

ARCTIC REWIND

10-year follow-up of patients with rheumatoid arthritis who received structured treatment-to-target therapy in the early disease phase.

Project Manager:
Espen A. Haavardsholm
WP4 - Managing comorbidities

ExeHeart

Better cardiovascular health for patients with inflammatory joint disease

Project Manager:
Anne Therese Tveter
WP5 - Innovative approaches to remote care

NOR Flare

Distance follow-up of patients with rheumatoid arthritis

Project Manager:
Anne Therese Tveter
WP2 - PPhenotyping for personalized medicine

Nor-vaC

Immunological response to COVID-19 vaccine in patients on immunosuppressive treatment

Project Manager:
Guro Løvik Goll
WP5 - Innovative approaches to remote care

ReMonit

remote monitoring of patients with spondyloarthritis

Project Manager:
Nina Østerås
WP5 - Innovative approaches to remote care

ReMonit Gout

Remote monitoring and management of gout

Project Manager:
Nina Østerås
WP1 - Optimized medical interventions

SQUEEZE

Maximizing the effect of prescription drugs in rheumatoid arthritis 

Project Manager:
Espen A. Haavardsholm

Publications

Publications taken from the National Science Archive (NVA):

Effects of tapering conventional synthetic disease-modifying antirheumatic drugs to drug-free remission versus stable treatment in rheumatoid arthritis (ARCTIC REWIND): 3-year results from an open-label, randomized controlled, non-inferiority trial

Kaja Eriksrud Kjørholt, Nina Paulshus Sundlisæter, Anna-Birgitte Aga, Joseph Sexton, Inge Christoffer Olsen, Hallvard Fremstad


The Lancet Rheumatology

2024

Clinical consequences of infliximab immunogenicity and the effect of proactive therapeutic drug monitoring: exploratory analyzes of the randomised, controlled NOR-DRUM trials

Marthe Kirkesæther Brun, Johanna Gehin, Kristin Reine Hammersbøen, David Warren, Rolf Klaasen, Joseph Sexton


The Lancet Rheumatology

2024

Does follow-up really matter? A convergent mixed methods study exploring follow-up across levels of care in rehabilitation of patients with rheumatic and musculoskeletal diseases

Gunnhild Berdal, Anne-Lene Sand-Svartrud, Anita Dyb Linge, Ann Margret Aasvold, Kjetil Tennebø, Siv Grødal Eppeland


Disability and Rehabilitation

2024

Effect of high-intensity interval training in physiotherapy primary care for patients with inflammatory arthritis: The ExeHeart randomized controlled trial

Kristine Røren Nordén, Anne Grete Semb, Hanne Dagfinrud, Jonny Hisdal, Joseph Sexton, Camilla Fongen


RMD Open

2024

Performance of the Rheumatoid Arthritis Impact of Disease (RAID) score in relation to flares in disease activity

Karen Holten, Nina Paulshus Sundlisæter, Joseph Sexton, Lena Bugge Nordberg, Till Uhlig, Tore Kristian Aaserud Kvien


RMD Open

2024

Developing and externally validating multinomial prediction models for methotrexate treatment outcomes in patients with rheumatoid arthritis: results from an international collaboration

Celina K. Gehringer, Glen P. Martin, Kimme L. Hyrich, Suzanne MM Verstappen, Joseph Sexton, Eirik Kristianslund


Journal of Clinical Epidemiology

2024

Incidence and outcome of COVID-19 following vaccine and hybrid immunity in patients on immunosuppressive therapy: identification of protective post-immunisation anti-RBD antibody levels in a prospective cohort study

Hilde Sofie Sager Ørbo, Kristin Reine Hammersbøen, Joseph Sexton, Ingrid Jyssum, Anne Therese Tveter, Ingrid Egeland Christensen


RMD Open

2024

Use of direct-acting anticoagulants (DOACs) delays surgery and is associated with increased mortality in hip fracture patients

Mads Sundet, Ulf Gunnar Sundin, Aasmund Godø, Kristian Sydnes, Haldor Valland, Joseph Sexton


European Journal of Trauma and Emergency Surgery

2024

Ultrasound evaluation contrasts clinical disease activity evaluation in rheumatoid arthritis patients with concomitant anxiety or depression

Brigitte Michelsen, Joseph Sexton, Tore Kristian Aaserud Kvien, Sella Aarestad Provan, Hilde Berner Hammer


Seminars in Arthritis & Rheumatism

2024

Agreement between patient-reported flares and clinically significant flare status in patients with rheumatoid arthritis in sustained remission: data from the ARCTIC REWIND trials

Karen Holten, Nina Paulshus Sundlisæter, Joseph Sexton, Kaja Eriksrud Kjørholt, Lena Bugge Nordberg, Tillmann Uhlig


RMD Open

2024

Interstitial lung disease in rheumatoid or psoriatic arthritis patients initiating biologics, and controls - data from five Nordic registries

Sella Aarrestad Provan, Eirik Klami Kristianslund, Brigitte Michelsen, Tillmann Uhlig, Joseph Sexton, Tore Kristian Aaserud Kvien


Journal of Rheumatology

2024

T cell responses to repeated SARS-CoV-2 vaccination and breakthrough infections in patients on TNF inhibitor treatment: a prospective cohort study

Asia-Sophia Fumika Michaela Wolf, Kristin Reine Hammersbøen, Hilde Sofie Sager Ørbo, Sabin Bhandari, Guri Solum, Ingrid Fadum Kjønstad


EBioMedicine

2024

Non-adherence to urate lowering therapy in gout after 5 years is related to poor outcomes - results from the NOR-Gout study

Tillmann Uhlig, Lars Fridtjof Karoliussen, Joseph Sexton, Sella Aarrestad Provan, Espen Andre Haavardsholm, Hilde Berner Hammer


Rheumatology

2024

Biological material for biomarker research in spondyloarthritis: mapping the availability in European rheumatology registries

Bente Glintborg, Mikkel Østergaard, Jacob Brauner Jørgensen, Johan Karlsson Wallman, Burkhard Möller, Michael John Nissen


Rheumatology

2024

Follow-Up of Patients With Axial Spondyloarthritis in Specialist Health Care With Remote Monitoring and Self-Monitoring Compared With Regular Face-to-Face Follow-Up Visits (the ReMonit Study): Protocol for a Randomized, Controlled Open-Label Noninferiority Trial

Inger Jorid Berg, Anne Therese Tveter, Gunnstein Bakland, Sarah Hakim, Eirik Kristianslund, Siri Lillegraven


JMIR Research Protocols

2023

Lifestyle factors predict gout outcomes: Results from the NOR-Gout longitudinal 2-year treat-to-target study

Till Uhlig, Lars Fridtjof Karoliussen, Joseph Sexton, Tore Kristian Aaserud Kvien, Espen A. Haavardsholm, Hilde Berner Hammer


RMD Open

2023

Adalimumab serum levels and anti-drug antibodies: associations to treatment response and drug survival in inflammatory joint diseases

Ingrid Jyssum, Johanna Gehin, Joseph Sexton, Eirik Kristianslund, Yi Hu, David Warren


Rheumatology

2023

Criterion Validity and Responsiveness of Estimated Cardiorespiratory Fitness Models in Patients with Inflammatory Joint Disease

Kristine Røren Nordén, Hanne Dagfinrud, Anne Grete Semb, Jonny Hisdal, George S. Metsios, Joseph Sexton


Journal of Clinical Medicine

2023

Course and predictors of work productivity in gout - results from the NOR-Gout longitudinal 2-year treat-to-target study

Till Uhlig, Lars Fridtjof Karoliussen, Joseph Sexton, Sella Aarrestad Provan, Tore Kristian Aaserud Kvien, Espen A. Haavardsholm


Rheumatology

2023

Remission, response, retention and persistence to treatment with disease-modifying agents in patients with rheumatoid arthritis: a study of harmonized Swedish, Danish and Norwegian cohorts

Helga Westerlind, Bente Glintborg, Hilde Berner Hammer, Saedis Saevarsdottir, Niels Steen Krogh, Merete Lund Hetland


RMD Open

2023

Effect of tapered versus stable treatment with tumor necrosis factor inhibitors on disease flares in patients with rheumatoid arthritis in remission: a randomised, open label, non-inferiority trial

Siri Lillegraven, Nina Paulshus Sundlisæter, Anna-Birgitte Aga, Joseph Sexton, Inge Christoffer Olsen, Åse Lexberg


Annals of the Rheumatic Diseases

2023

Associations between pain sensitization and measures of physical function in people with hand osteoarthritis: Results from the Nor-Hand study

Marthe Gløersen, Pernille Steen Pettersen, Tuhina Neogi, Joseph Sexton, Tore Kristian Aaserud Kvien, Hilde Berner Hammer


Osteoarthritis and Cartilage

2023

Calprotectin, a sensitive marker of inflammation, is robustly assessed in plasma from patients with early or established rheumatoid arthritis by use of different laboratory methods

Hilde Berner Hammer, Sigve Lars Pedersen, Maria Karolina Jonsson, Linda Mathsson-Alm, Isabel Gehring, Joseph Sexton


Scandinavian Journal of Clinical and Laboratory Investigation

2023

Discontinuation rate of sulfasalazine, leflunomide and methotrexate due to adverse events in a real-life setting (NOR-DMARD)

Mielnik Pawel, Joseph Sexton, Karen Minde Fagerli, Gunnstein Bakland, Yi Hu, Eirik Kristianslund


Rheumatology - Advances in Practice (Rheumap)

2023

Beliefs about medicines in gout patients: results from the NOR-Gout 2-year study

Till Uhlig, Lars Fridtjof Karoliussen, Joseph Sexton, Tore Kristian Aaserud Kvien, Espen A. Haavardsholm, WJ Taylor


Scandinavian Journal of Rheumatology

2023

Discontinuation of Conventional Synthetic Disease-Modifying Antirheumatic Drugs in Patients with Rheumatoid Arthritis and Excellent Disease Control

Siri Lillegraven, Nina Paulshus Sundlisæter, Anna-Birgitte Aga, Joseph Sexton, Daniel H. Solomon, Désirée Van Der Heijde


Journal of the American Medical Association (JAMA)

2023

Associations between cardiovascular risk factors, disease activity and cardiorespiratory fitness in patients with inflammatory joint disease: a cross-sectional analysis

Kristine Røren Nordén, Anne Grete Semb, Hanne Dagfinrud, Jonny Hisdal, Sigrid Ødegård, Joseph Sexton


BMC sports science, medicine and rehabilitation

2023

Bridging gaps across levels of care in rehabilitation of patients with rheumatic and musculoskeletal diseases: Results from a stepped-wedge cluster randomized controlled trial

Gunnhild Berdal, Anne-Lene Sand-Svartrud, Anita Dyb Linge, Ann Margret Aasvold, Kjetil Tennebø, Siv Grødal Eppeland


Clinical Rehabilitation

2023

HLA-DQ2 is associated with anti-drug antibody formation to infliximab in patients with immune-mediated inflammatory diseases

Marthe Kirkesæther Brun, Kristin Reine Hammersbøen, Marte Kathrine Viken, Grethe-Elisabeth Stenvik, Rolf Klaasen, Johanna Gehin


Journal of Internal Medicine

2023

Patient Experienced Symptom State in rheumatoid arthritis: sensitivity to change in disease activity and impact

Catia Duarte, Tore Kristian Aaserud Kvien, Joseph Sexton, Eduardo Santos, Maarten De Wit, Laure Gossec


Rheumatology

2023

Treatment Response to Tumor Necrosis Factor Inhibitors and Methotrexate Monotherapy in Adults With Juvenile Idiopathic Arthritis: Data From NOR-DMARD

Imane Bardan, Karen Minde Fagerli, Joseph Sexton, Tore Kristian Aaserud Kvien, Gunnstein Bakland, Mielnik Pawel


Journal of Rheumatology

2022

Haematological malignancies in patients with psoriatic arthritis overall and treated with TNF inhibitors: a Nordic cohort study

Rene Lindholm Cordtz, Johan Askling, Benedicte Delcoigne, Karin E. Smedby, Eva Baecklund, Christine Ballegaard


RMD Open

2022

Identification of SNPs associated with methotrexate treatment outcomes in patients with early rheumatoid arthritis

Shrikant Kolan, Gaoyang Li, Franco Grimolizzi, Joseph Sexton, Tore Kristian Kvien, Guro Løvik Goll


Frontiers in Pharmacology

2022

Four SARS-CoV-2 vaccine doses or hybrid immunity in patients on immunosuppressive therapies: a Norwegian cohort study

Kristin H. Bjørlykke, Hilde Sofie Sager Ørbo, Anne Therese Tveter, Ingrid Jyssum, Joseph Sexton, Trung Tran


The Lancet Rheumatology

2022

All-cause and cause-specific mortality in rheumatoid arthritis, psoriatic arthritis and axial spondyloarthritis: a nationwide registry study

Anne Mirjam Kerola, Amirhossein Kazemi, Silvia Christin Hellerud Rollefstad, Siri Lillegraven, Joseph Sexton, Grunde Wibetoe


Rheumatology

2022

Interventions for osteoarthritis pain: A systematic review with network meta-analysis of existing Cochrane reviews

Geir Smedslund, Ingvild Kjeken, Frauke Musial, Joseph Sexton, Nina Østerås


Osteoarthritis and Cartilage Open

2022

Immunogenicity and safety of a three-dose SARS-CoV-2 vaccination strategy in patients with immune-mediated inflammatory diseases on immunosuppressive therapy

Silje Watterdal Syversen, Ingrid Jyssum, Anne Therese Tveter, Joseph Sexton, Ingrid Egeland Christensen, Trung Tran


RMD Open

2022

Fluctuation and change of serum urate levels and flares in gout: results from the NOR-Gout study

Till Uhlig, Lars Fridtjof Karoliussen, Joseph Sexton, Tore Kristian Kvien, Espen A. Haavardsholm, F. Perez-Ruiz


Clinical Rheumatology

2022

The persistence of anti-Spike antibodies following two SARS-CoV-2 vaccine doses in patients on immunosuppressive therapy compared to healthy controls—a prospective cohort study

Ingrid Egeland Christensen, Ingrid Jyssum, Anne Therese Tveter, Joseph Sexton, Trung Tran, Siri Mjaaland


BMC Medicine

2022

A Clinical Audit of Cardiovascular Risk Factors and Disease in Patients with Rheumatoid Arthritis - SURF-RA

Anne Grete Semb, Eirik Ikdahl, Anne M. Kerola, Grunde Wibetoe, Joseph Sexton, Cynthia S. Crowson


Mediterranean Journal of Rheumatology

2022

Risk factors for anti-drug antibody formation to infliximab: Secondary analyzes of a randomized controlled trial

Marthe Kirkesæther Brun, Guro Løvik Goll, Kristin Kaasen Jørgensen, Joseph Sexton, Johanna Elin Gehin, Øystein Sandanger


Journal of Internal Medicine

2022

Immunogenicity and Safety of Standard and Third-Dose SARS-CoV-2 Vaccination in Patients Receiving Immunosuppressive Therapy

Silje Watterdal Syversen, Ingrid Jyssum, Anne Therese Tveter, Trung Tran, Joseph Sexton, Sella Aarrestad Provan


Arthritis & Rheumatology

2022

Oral anticoagulant treatment in rheumatoid arthritis patients with atrial fibrillation results of an international audit

Anne Grete Semb, Silvia Christin Hellerud Rollefstad, Joseph Sexton, Eirik Ikdahl, Cynthia S. Crowson, Piet van Riel


International journal of cardiology: Heart and Vasculature (IJCHA)

2022

An international audit of the management of dyslipidaemia and hypertension in patients with rheumatoid arthritis: results from 19 countries

Silvia Christin Hellerud Rollefstad, Eirik Ikdahl, Grunde Wibetoe, Joseph Sexton, Cynthia S. Crowson, Piet van Riel


European Heart Journal (EHJ) - Cardiovascular Pharmacotherapy

2022

Using observational study data as an external control group for a clinical trial: an empirical comparison of methods to account for longitudinal missing data

Vibeke Norvang, Espen A. Haavardsholm, Sara K. Tedeschi, Houchen Lyu, Joseph Sexton, Maria Dahl Mjaavatten


BMC Medical Research Methodology

2022

Psoriatic arthritis, axial spondyloarthritis and rheumatoid arthritis in Norway: nationwide prevalence and use of biologic agents

AM Kerola, Silvia Christin Hellerud Rollefstad, Amirhossein Kazemi, Grunde Wibetoe, Joseph Sexton, N. Mars


Scandinavian Journal of Rheumatology

2022

One- and 2-year flare rates after treat-to-target and tight-control therapy of gout: results from the NOR-Gout study

Till Uhlig, Lars Fridtjof Karoliussen, Joseph Sexton, Tore Kristian Kvien, Espen A. Haavardsholm, Fernando Perez-Ruiz


Arthritis Research & Therapy

2022

Associations between quality of health care and clinical outcomes in patients with rheumatic and musculoskeletal diseases: a rehabilitation cohort study

Anne-Lene Sand-Svartrud, Gunnhild Berdal, Maryam Azimi, Ingvild Bø, Turid Nygaard Dager, Siv Grødal Eppeland


BMC Musculoskeletal Disorders

2022

Inflammation and biologic therapy in patients with rheumatoid arthritis achieving versus not achieving ACR/EULAR Boolean remission in a treat-to-target study

Nina Beate Paulshus Sundlisæter, Ulf Gunnar Sundin, Anna-Birgitte Aga, Joseph Sexton, Hilde Berner Hammer, Till Uhlig


RMD Open

2022

Identifying long-term and imminent suicide predictors in a general population and a clinical sample with machine learning

Lloyd D. Balbuena, Marilyn Baetz, Joseph Sexton, Douglas Harder, Cindy Xin Feng, Kerstina Boctor


BMC Psychiatry

2022

Effect of high-intensity exercise on cardiorespiratory fitness, cardiovascular disease risk and disease activity in patients with inflammatory joint disease: Protocol for the ExeHeart randomized controlled trial

Kristine Røren Nordén, Hanne Dagfinrud, Anne Grete Semb, Jonny Hisdal, Kirsten Kilvik Viktil, Joseph Sexton


BMJ Open

2022

Associations of Body Mass Index With Pain and the Mediating Role of Inflammatory Biomarkers in People With Hand Osteoarthritis

Marthe Gløersen, Pernille Steen Pettersen, Tuhina Neogi, S. Reza Jafarzadeh, Maria Vistnes, Christian S. Thudium


Arthritis & Rheumatology

2022

Humoral and cellular immune responses to two and three doses of SARS-CoV-2 vaccines in rituximab-treated patients with rheumatoid arthritis: a prospective, cohort study

Ingrid Jyssum, Hassen Kared, Trung Tran, Anne Therese Tveter, Sella Aarrestad Provan, Joseph Sexton


The Lancet Rheumatology

2021

Two-year reduction of dual-energy CT urate deposits during a treat-to-target strategy in gout in the NOR-Gout longitudinal study.

Till Uhlig, Tron Hovind Eskild, Lars Fridtjof Karoliussen, Joseph Sexton, Tore Kristian Kvien, Espen A. Haavardsholm


Rheumatology

2021

Serum etanercept concentrations in relation to disease activity and treatment response assessed by ultrasound, biomarkers and clinical disease activity scores: results from a prospective observational study of patients with rheumatoid arthritis.

Johanna Elin Gehin, Silje Watterdal Syversen, David Warren, Guro Løvik Goll, Joseph Sexton, Nils Bolstad


RMD Open

2021

Effect of Therapeutic Drug Monitoring vs Standard Therapy During Maintenance Infliximab Therapy on Disease Control in Patients With Immune-Mediated Inflammatory Diseases: A Randomized Clinical Trial

Silje Watterdal Syversen, Kristin Kaasen Jørgensen, Guro Løvik Goll, Marthe Kirkesæther Brun, Øystein Sandanger, Kristin Reine Hammersbøen


Journal of the American Medical Association (JAMA)

2021

Development and validation of a patient-reported outcome measure for systemic sclerosis: the EULAR Systemic Sclerosis Impact of Disease (ScleroID) questionnaire.

Mike Oliver Becker, Rucsandra Dobrota, Alexandru Garaiman, Rudolf Debelak, Kim Fligelstone, Ann Tyrrell Kennedy


Annals of the Rheumatic Diseases

2021

Incidence, sociodemographic factors and treatment penetration of rheumatoid arthritis and psoriatic arthritis in Norway.

Anne Mirjam Kerola, Joseph Sexton, Grunde Wibetoe, Silvia Christin Hellerud Rollefstad, Cynthia Sue Crowson, Nina Mars


Seminars in Arthritis & Rheumatism

2021

Diabetes mellitus and cardiovascular risk management in patients with rheumatoid arthritis: an international audit.

Anne Grete Semb, Silvia Christin Hellerud Rollefstad, Eirik Ikdahl, Grunde Wibetoe, Joseph Sexton, Cindy Crowson


RMD Open

2021

Fatigue in patients with early rheumatoid arthritis undergoing treat-to-target therapy: predictors and response to treatment

Karen Holten, Nina Beate Paulshus Sundlisæter, Siri Lillegraven, Joseph Sexton, Lena Kristine Bugge Nordberg, Ellen Moholt


Annals of the Rheumatic Diseases

2021

Comparison of 2 Postoperative Therapy Regimens After Trapeziectomy due to Osteoarthritis: A Randomized, Controlled Trial

Merete Hermann, Tove Nilsen, Åshild Hove, Lars Eilertsen, Ida Kristin Bos-Haugen, Joseph Sexton


Journal of Hand Surgery-American Volume

2021

Serum golimumab concentration and anti-drug antibodies are associated with treatment response and drug survival in patients with inflammatory joint diseases: data from the NOR-DMARD study

Johanna Elin Gehin, David Warren, Silje Watterdal Syversen, Elisabeth Lie, Joseph Sexton, Liz Paucar Loli


Scandinavian Journal of Rheumatology

2021

Serious infections in patients with rheumatoid arthritis and psoriatic arthritis treated with tumor necrosis factor inhibitors: data from register linkage of the NOR-DMARD study

Ingrid Egeland Christensen, Siri Lillegraven, Mielnik Pawel, Gunnstein Bakland, Liz Paucar Loli, Joseph Sexton


Annals of the Rheumatic Diseases

2021

Risk of solid cancers overall and by subtypes in patients with psoriatic arthritis treated with TNF inhibitors - a Nordic cohort study

Karin Hellgren, Christine Ballegaard, Bénédicte Delcoigne, René Cordtz, Dan C. Nordström, Kalle Aaltonen


Rheumatology

2021

Trajectories of change in symptom severity in patients with fibromyalgia: exploratory analyzes of a randomized controlled trial

Trond Haugmark, Kåre Birger Hagen, Sella Aarrestad Provan, Joseph Sexton, Heidi Andersen Zangi


Rheumatology International

2021

12-month results from the real-life observational treat-to-target and tight-control therapy NOR-Gout study: Achievements of the urate target levels and predictors of obtaining this target

Till Uhlig, Lars Fridtjof Karoliussen, Joseph Sexton, Tove Borgen, Espen A. Haavardsholm, Tore Kristian Kvien


RMD Open

2021

Degree of arterial stiffness is comparable across inflammatory joint disease entities

Friedrich Konstantin, Silvia Christin Hellerud Rollefstad, Eirik Ikdahl, Grunde Wibetoe, Joseph Sexton, Jonny Hisdal


Scandinavian Journal of Rheumatology

2021

Effect of Half-Dose vs Stable-Dose Conventional Synthetic Disease-Modifying Antirheumatic Drugs on Disease Flares in Patients with Rheumatoid Arthritis in Remission: The ARCTIC REWIND Randomized Clinical Trial

Siri Lillegraven, Nina Beate Paulshus Sundlisæter, Anna-Birgitte Aga, Joseph Sexton, Inge Christoffer Olsen, Hallvard Fremstad


Journal of the American Medical Association (JAMA)

2021

Value of MRI and ultrasound for prediction of therapeutic response and erosive progression in patients with early rheumatoid arthritis managed by an aggressive treat-to-target strategy

Ulf Gunnar Sundin, Nina Beate Paulshus Sundlisæter, Anna-Birgitte Aga, Joseph Sexton, Lena Kristine Bugge Nordberg, Hilde Berner Hammer


RMD Open

2021

Effect of Therapeutic Drug Monitoring vs Standard Therapy During Infliximab Induction on Disease Remission in Patients With Chronic Immune-Mediated Inflammatory Diseases: A Randomized Clinical Trial

Silje Watterdal Syversen, Guro Løvik Goll, Kristin Kaasen Jørgensen, Øystein Sandanger, Joseph Sexton, Inge Christoffer Olsen


Journal of the American Medical Association (JAMA)

2021

Prediction of cardiovascular events in rheumatoid arthritis using risk age calculations: evaluation of concordance across risk age models

Grunde Wibetoe, Joseph Sexton, Eirik Ikdahl, Silvia Christin Hellerud Rollefstad, George D. Kitas, Piet van Riel


Arthritis Research & Therapy

2020

Drug retention, inactive disease and response rates in 1860 patients with axial spondyloarthritis initiating secukinumab treatment: routine care data from 13 registries in the EuroSpA collaboration

Brigitte Michelsen, Ulf Lindström, Catalin Codreanu, Adrian Ciurea, Jakub Zavada, Anne Gitte Loft


RMD Open

2020

Therapeutic drug monitoring of infliximab compared to standard clinical treatment with infliximab: study protocol for a randomised, controlled, open, parallel-group, phase IV study (The NOR-DRUM study)

Silje Watterdal Syversen, Guro Løvik Goll, Kristin Kaasen Jørgensen, Inge Christoffer Olsen, Øystein Sandanger, Johanna Elin Gehin


Trials

2020

Trajectories of fatigue in actively treated patients with established rheumatoid arthritis starting biologic DMARD therapy

Sella Aarrestad Provan, Brigitte Michelsen, Joseph Sexton, Till Uhlig, Hilde Berner Hammer


RMD Open

2020

Does Older Age have an Impact on Rituximab Efficacy and Safety? Results from the NOR-DMARD Register

Mielnik Pawel, Joseph Sexton, Elisabeth Lie, Gunnstein Bakland, Liz Paucar Loli, Eirik Kristianslund


Drugs & Aging

2020

Fatigue is cross-sectionally not associated with objective assessments of inflammation, but changes in fatigue are associated with changes of disease activity assessments during biologic treatment of patients with established rheumatoid arthritis

Hilde Berner Hammer, Brigitte Michelsen, Joe Sexton, Till Uhlig, Sella Aarrestad Provan


Clinical Rheumatology

2020

Efficacy and safety of CT-P13 in inflammatory bowel disease after switching from originator infliximab: Exploratory analyzes from the NOR-SWITCH main and extension trials

Kristin Kaasen Jørgensen, Guro Løvik Goll, Joseph Sexton, Nils Bolstad, Inge Christoffer Olsen, Øivind Wessel Asak


BioDrugs

2020

Achievement of Remission in Two Early Rheumatoid Arthritis Cohorts Implementing Different Treat-to-Target Strategies

Vibeke Norvang, Gina Charlotte Hetland Brinkmann, Kazuki Yoshida, Siri Lillegraven, Anna-Birgitte Aga, Joseph Andrew Sexton


Arthritis & Rheumatology

2020

Trends in All-Cause and Cardiovascular Mortality in Patients With Incident Rheumatoid Arthritis: A 20-year Follow-Up Matched Case-Cohort Study

Sella Aarrestad Provan, Siri Lillegraven, Joseph Sexton, Kristin Angel, Cathrine Austad, Espen A. Haavardsholm


Rheumatology

2019

Effects of long-term statin treatment on coronary atherosclerosis in patients with inflammatory joint diseases

Mona Svanteson, Silvia Christin Hellerud Rollefstad, Nils-Einar Kløw, Jonny Hisdal, Eirik Ikdahl, Joseph Sexton


PLOS ONE

2019

Associations between certolizumab pegol serum levels, anti-drug antibodies and treatment response in patients with inflammatory joint diseases: data from the NOR-DMARD study

Johanna Elin Gehin, Guro Løvik Goll, David John Warren, Silje Watterdal Syversen, Joseph Sexton, Eldri Kveine Strand


Arthritis Research & Therapy

2019

Peptidylarginine deiminase 4 (PAD4) activity in early rheumatoid arthritis

Maria Karolina Jonsson, Tomasz Tadeusz Kantyka, Katherine Falkowski, Ardita Aliko, Anna-Birgitte Aga, Siri Lillegraven


Scandinavian Journal of Rheumatology

2019

Four-year follow-up of inflammatory arthropathy patients treated with golimumab: Data from the observational multicentre NOR-DMARD study

Brigitte Michelsen, Joseph Sexton, Ada Wierød, Gunnstein Bakland, Erik Rødevand, Frode Krøll


Seminars in Arthritis & Rheumatism

2019

Assessing synovitis in the hands in patients with rheumatoid arthritis by ultrasound: an agreement study exploring the most inflammatory active side from two Norwegian trials

Lene Terslev, Robin Christensen, Anna-Birgitte Aga, Joseph Sexton, Espen A. Haavardsholm, Hilde Berner Hammer


Arthritis Research & Therapy

2019

Swollen, but not tender joints, are independently associated with ultrasound synovitis: Results from a longitudinal observational study of patients with established rheumatoid arthritis

Hilde Berner Hammer, Brigitte Michelsen, Joseph Sexton, Ida Kristin Haugen, Sella Aarrestad Provan, Espen A. Haavardsholm


Annals of the Rheumatic Diseases

2019

Long‐term efficacy and safety of biosimilar infliximab (CT‐P13) after switching from originator infliximab: Open‐label extension of the NOR‐SWITCH trial

Guro Løvik Goll, Kristin Kaasen Jørgensen, Joseph Sexton, Inge Christoffer Olsen, Nils Bolstad, Espen A. Haavardsholm


Journal of Internal Medicine

2019

Comparing the disease course of patients with seronegative and seropositive rheumatoid arthritis fulfilling the 2010 ACR/EULAR classification criteria in a treat-to-target setting: 2-year data from the ARCTIC trial

Lena Kristine Bugge Nordberg, Siri Lillegraven, Anna-Birgitte Aga, Joseph Sexton, Inge Christoffer Olsen, Elisabeth Lie


RMD Open

2018

Can disease activity in patients with psoriatic arthritis be adequately assessed by a modified Disease Activity index for PSoriatic Arthritis (DAPSA) based on 28 joints?

Brigitte Michelsen, Joseph Sexton, Josef Sebastian Smolen, Daniel Aletaha, Niels Steen Krogh, Desirée van der Heijde


Annals of the Rheumatic Diseases

2018

Tender joint count may not reflect inflammatory activity in established rheumatoid arthritis patients: results from a longitudinal study

Hilde Berner Hammer, Brigitte Michelsen, Sella Aarrestad Provan, Joseph Sexton, Jon Lampa, Till Uhlig


Arthritis care & research

2018

DAPSA and ultrasound show different perspectives of psoriatic arthritis disease activity: results from a 12-month longitudinal observational study in patients starting treatment with biological disease-modifying antirheumatic drugs

Silva Pukšić, Pernille Bolton-King, Joseph Sexton, Brigitte Michelsen, Tore Kristian Kvien, Hilde Berner Hammer


RMD Open

2018

Comparative analyzes of responsiveness between the Rheumatoid Arthritis Impact of Disease score, other patient-reported outcomes and disease activity measures: secondary analyzes from the ARCTICstudy

Karen Holten, Joseph Sexton, Tore Kristian Kvien, Anna-Birgitte Aga, Espen A. Haavardsholm


RMD Open

2018

Predicting achievement of the treatment targets at 6 months from 3-month response levels in rheumatoid arthritis: data from real-life follow-up in the NOR-DMARD study

Vibeke Norvang, Joseph Sexton, Eirik Kristianslund, Inge Christoffer Olsen, Till Uhlig, Gunnstein Bakland


RMD Open

2018

A Key Characteristic of Sex Differences in the Developing Brain: Greater Variability in Brain Structure of Boys than Girls

Lara M. Wierenga, Joseph Sexton, Petter Laake, Jay N. Giedd, Christian Krog Tamnes


Cerebral Cortex

2018

Is synovial hypertrophy without Doppler activity sensitive to change? Post-hoc analysis from a rheumatoid arthritis ultrasound study

Lene Terslev, Mikkel Østergaard, Joseph Sexton, Hilde Berner Hammer


Arthritis Research & Therapy

2018

The impact of ultrasound on the use and efficacy of intraarticular glucocorticoid injections in early rheumatoid arthritis: Secondary analyzes from a randomized trial examining the benefit of ultrasound in a clinical tight control regimen

Lena Kristine Bugge Nordberg, Siri Lillegraven, Anna-Birgitte Aga, Joseph Sexton, Elisabeth Lie, Hilde Berner Hammer


Arthritis & Rheumatology

2018

The role of anti-citrullinated protein antibody reactivities in an inception cohort of patients with rheumatoid arthritis receiving treat-to-target therapy

Maria Karolina Jonsson, Aase Haj Hensvold, Monika Hansson, Anna-Birgitte Aga, Joseph Sexton, Linda Mathsson-Alm


Arthritis Research & Therapy

2018

Health-related quality of life in patients with psoriatic and rheumatoid arthritis: Data from the prospective multicentre NOR-DMARD study compared with Norwegian general population controls

Brigitte Michelsen, Till Uhlig, Joseph Sexton, Desirée van der Heijde, Hilde Berner Hammer, Eirik Kristianslund


Annals of the Rheumatic Diseases

2018

Do depression and anxiety reduce the likelihood of remission in rheumatoid arthritis and psoriatic arthritis? Data from the prospective multicentre NOR-DMARD study

Brigitte Michelsen, Eirik Kristianslund, Joseph Sexton, Hilde Berner Hammer, Karen Minde Fagerli, Elisabeth Lie


Annals of the Rheumatic Diseases

2017

The effect of training in mindfulness and affect consciousness on the therapeutic environment for patients with psychoses: An exploratory intervention study

Birgit Hilde Kaisa Eliassen, Tore Sørlie, Joseph Sexton, Tordis Sørensen Høifødt


Scandinavian Journal of Caring Sciences

2016

Importance of doctors' age for prescribed amount of benzodiazepines

Jørgen Gustav Bramness, Trine Bjørner, Joseph Sexton


Norwegian Pharmaceutical Journal

2015

Dietary patterns among Norwegian 2-year-olds in 1999 and in 2007 and associations with child and parent characteristics

Anne Lene Kristiansen, Britt Lande, Joseph Sexton, Lene Frost Andersen


British Journal of Nutrition

2013